DailyTickers

ARWR — Arrowhead Pharmaceuticals, Inc.

NASDAQ · Healthcare · August 28, 2026
$90.00 +1.72% Wait for regular-session confirmation Biotechnology Score 58 C+
$12.71B
Market Cap
857,500
Volume
N/A
Fwd P/E
1.294
Beta
N/A
52W Range
9.1%
Short Interest
$110.18
Analyst Target
N/A
EV/EBITDA
ARWR Chart
Click to enlarge

Verdict Express

C+ Neutral Moderate confidence

Arrowhead commercializes REDEMPLO (plozasiran) and is building the launch while pursuing label expansion and the SHASTA and YOSEMITE programs. Commercial execution now matters alongside clinical outcomes.. Wait for regular-session confirmation. Wait state: Break $89.59 with confirmed volume.

Why Buy

  • Revenue growth: 171.0%; earnings growth: 0.0%
  • Cash $1.60B versus debt $1.38B
  • Defined confirmation: Break $89.59 with confirmed volume

Why Avoid

  • Wait state: Break $89.59 with confirmed volume.
  • First-target reward/risk at confirmation: 1.49R
  • REDEMPLO launch execution, sNDA timing and SHASTA/YOSEMITE trial outcomes remain binary.

Business Overview

Arrowhead commercializes REDEMPLO (plozasiran) and is building the launch while pursuing label expansion and the SHASTA and YOSEMITE programs. Commercial execution now matters alongside clinical outcomes.

Recent News

2026-08-24
Arrowhead Pharmaceuticals to Present New Clinical Data at the European Society of Cardiology Congress neutral
Context only; no trade conclusion is drawn from this headline.
Business Wire
2026-08-20
Arrowhead Pharmaceuticals Insider Sold Shares Worth $1,012,680, According to a Recent SEC Filing neutral
Context only; no trade conclusion is drawn from this headline.
MT Newswires
2026-08-17
Arrowhead Pharmaceuticals' Redemplo Now Available in Germany for FCS Patients neutral
Context only; no trade conclusion is drawn from this headline.
MT Newswires
2026-08-05
ARWR: Acquires PRV for sNDA Submission for Plozasiran in sHTG negative
Potential downside risk; the headline alone does not quantify the impact.
Zacks Small Cap Research
2026-08-05
Arrowhead Pharmaceuticals Inc (ARWR) (Q3 2026) Earnings Call Highlights: Strong Phase III Data ... neutral
Context only; no trade conclusion is drawn from this headline.
GuruFocus.com
2026-08-04
Arrowhead Pharmaceuticals Q3 Earnings Call Highlights neutral
Context only; no trade conclusion is drawn from this headline.
MarketBeat

Fundamentals

MetricValueSignal
Revenue (TTM)$669.5M171.0% YoY
EBITDAN/ANot meaningful / unavailable
Gross Margin100.0%Reported
Operating Margin-226.0%Loss-making
Net Margin-47.8%Negative
ROE-55.2%Capital efficiency
Cash$1.60BLiquidity
Debt$1.38BBalance-sheet claim
Forward P/EN/ANo estimate substituted
Intrinsic-value modelN/AFail-closed: insufficient inputs
Value / quality panel0 positive / 5 negative / 0 neutralbearish / confidence 48
Analyst Mean Target$110.18Consensus, not a guarantee

Earnings History

QuarterEPS ActualEPS Est.SurpriseRevenue
3Q2025$-0.18$-0.16-14.5%-
4Q2025$0.22$-0.37159.9%-
1Q2026$-0.93$-1.1116.0%-
2Q2026$-1.36$-1.23-10.4%-

2/4 captured quarters beat estimates — Next: 2026-11-24T20:00:00Z

Insiders & Institutions

3.7%
Insider Own.
85.6%
Institution Own.

No structured transaction table was captured; aggregate counts are not used.

Capital Structure & Dilution

141.3M
Shares Out.
See filing review
Authorized
high
Dilution Risk

Warrants

SeriesTypeStrikeSharesExp.DilutionStatus
January 2026Pre-fundedN/A1.550MN/AIssued in the 2026 financingOutstanding
LegacyOutstanding warrantsN/A917,441N/ALegacy overhang disclosed in the 10-QOutstanding

Active ATM Program

Authorized: $500M program | Used: $76.1M gross through nine months | Remaining: Verify the latest 10-Q before entry

A $500M ATM remains relevant after $76.1M of gross issuance. January financing raised $230M and included pre-funded warrants; $700M of 0% convertible notes mature in 2032.

SEC Filings Review

Official filings were reviewed through 2026-08-28; the table lists the decision-relevant documents rather than every routine filing. The C+ grade describes the full dossier; the trade state (wait) is a separate timing decision.

DateFormAccessionWhat the filing changes
2026-08-0410-Q0000879407-26-000057Confirms $1.60B of liquidity, ATM usage and commercial/clinical spending.
2026-01-09424B50001193125-26-007968Documents the January equity and pre-funded-warrant financing.
2025-12-11S-3ASR0001193125-25-314755Establishes the shelf and ATM capacity.
2026-01-09424B50001193125-26-007962Documents the $700M 0% convertible notes due 2032.

Contrarian checks

Short Interest

9.1%
SI % Float
8.79
Days to Cover
N/A
CTB

Current snapshot only; no acceleration claim without a comparable historical series.

Options / Derivatives

14,586
Call OI
8,305
Put OI
1.76
C/P Ratio
$75.00
Max Pain
N/A
IV Mean

Unusual Activity: No unusual activity confirmed

Technical Analysis

RSI (14)56.2
EMA 20$87.04
EMA 50$83.61
EMA 200$66.68
MACD1.526
Signal1.729
ATR (14)$3.20
WyckoffTransitional
RSI 56.2 WAIT Wait for regular-session confirmation
Supports: $60.61 / $37.20 / $15.01
Resistances:

Technical Setup

Wait for regular-session confirmation. Required confirmation: Break $89.59 with confirmed volume. Available moving averages are shown with their provider type.

Performance & Benchmarks

33.4%
YTD
306.6%
1Y
N/A — insufficient point-in-time history
3Y
Not calculated without aligned benchmark bars.
Alpha

Macro Context

IndicatorValueSignal
Market regimeRisk-on 0.79Trend support, not a timing trigger
VIX14.51Low current protection price

Regime: risk-on

The broad regime supports long setups, but rates and ticker-specific confirmation override the label.

Risk Analysis

Risk Profile: High

Dilution: high; beta: 1.29; insider signal: unavailable.

Trade Structure

High
  • First-target reward/risk at confirmation: 1.49R
  • Wait state: Break $89.59 with confirmed volume.
Probability
Impact
Break $89.59 with confirmed volume

Capital and Dilution

High
  • A $500M ATM remains relevant after $76.1M of gross issuance. January financing raised $230M and included pre-funded warrants; $700M of 0% convertible notes mature in 2032.
  • REDEMPLO launch execution, sNDA timing and SHASTA/YOSEMITE trial outcomes remain binary.
  • Liquidity covers at least twelve months, but the filing does not justify an invented multi-year runway.
Probability
Impact
SEC review: high dilution risk. Filings and accessions are listed below.

Positioning

Low
  • 0 insider buys vs 0 sells
  • Short interest: 9.1%
Probability
Impact
Positioning is context, not a standalone trigger.

Risk Synthesis

A precise stop does not make a setup valid. Entry location, normal volatility, event risk and reachable resistance decide whether the risk is paid.

Social Radar

Stocktwits
30
neutral
12451 watchers; not used as a trigger.
Aggregate sentiment
2
positive
Confidence 15.5%.

Pump & Dump Score: 1/6

Clean
No recent halt flag
Short interest below 20%
SEC-reviewed dilution risk is high

Capital Flow

N/A
Net Flow
N/A
Institutional
N/A
Retail
40.0%
Dark Pool %

No directional flow claim is made when detailed, aligned flow data is unavailable.

Trade Idea

WAIT — Wait state: Break $89.59 with confirmed volume.
Entry Zone
$88.60
Original zone $88.00-$89.20. Break $89.59 with confirmed volume. At the conservative $89.59 confirmation price, TP1 pays 1.49R.
Stop Loss
$83.68
-6.19% risk
Target 1
$98.40
10.31% upside
Risk/Reward
Confirmation TP1 1:1.49; original plan 1:1.67
10 trading sessions

Thesis

Wait for regular-session confirmation. Monitor break $89.59 with confirmed volume; no market order and no chase outside the zone.

Catalysts

  • Crowded-positioning pressure is flagged, but it is not an entry trigger.
  • Business Wire — - Detailed results from the Phase 3 SHASTA-3 and SHASTA-4 Studies of Plozasiran in Patients with Severe Hypertriglyceridemia will be presented as a HOT LINE Late-Breaking Science Session on August 30,...
  • Break $89.59 with confirmed volume

Invalidation

  • Below $83.68
  • Wait state: Break $89.59 with confirmed volume.
  • Any earnings, clinical, regulatory or financing event before entry requires a fresh review.

Global Score

C+ Healthcare Neutral

Key Takeaways — Positive

  • Defined trigger: Break $89.59 with confirmed volume
  • Dilution assessment after filing review: high
  • Revenue growth: 171.0%

Key Takeaways — Risks

  • Wait state: Break $89.59 with confirmed volume.
  • First-target R/R at confirmation: 1.49R
  • REDEMPLO launch execution, sNDA timing and SHASTA/YOSEMITE trial outcomes remain binary.
  • Liquidity covers at least twelve months, but the filing does not justify an invented multi-year runway.

Mindset Tip

Wait for confirmation and preserve the invalidation.

Disclaimer

This analysis is provided for informational and educational purposes only. It does not constitute financial advice, investment recommendation, or solicitation to buy or sell any security.

Past performance is not indicative of future results. All investments involve risk, including the possible loss of principal. Always conduct your own research and consult a licensed financial advisor before making investment decisions.

Data comes from point-in-time market snapshots, company filings, Yahoo Finance, SEC EDGAR, and public market data. Accuracy is not guaranteed.

Verdict Business News Fundamentals Earnings Insiders Capital SEC Review Technical Perf Risks Social Flow Trade Score